Lancet commission identifies 17 major threats to global health through 2100

2026-10-10

The commission identified 17 threats that could cause major health losses over the next 75 years, including climate change, pandemics, malnutrition, inequality and antimicrobial resistance.
The report says malicious use of AI, including to create bioweapons, and nuclear conflict leading to nuclear famine could carry risks of human extinction.
The assessment uses disability-adjusted life years to estimate health losses across 204 countries and territories; it is not intended to rank the threats.
The authors say the threats interact and urge coordinated action, while stressing that there are practical ways to reduce every risk.